LISTING THE SCORES OF NATURAL WEIGHT-REDUCING INSULIN SENSITIZERS:

 neil.burman@gmail.com

 one of the great frauds of the corporate Prescription Drug Innovators- backed by their tools the FDA and the other Drug regulators, academics and political lobbyists they fund – is to omit to mention the natural nutrients that invariably do better than the patented prescription drugs they want mimicked.

Or they  hide behind the FDA smokescreen that natural products cannot be recommended until they have undergone far more rigorous trials than was required of modern designer drugs- which moderns rarely stand the test of time – efficacy, necessity and safety- with chronic use.

A classical example is the entries that one is led to on search for Insulin Sensitizers: eg – apart from metformin- many sites list only designer drugs eg the dangerous pioglitazone (Actos) or rosiglitazone (Avandia)- eg in Self-management of Diabetes  , and New Drugs for Type 2 Diabetes  and US Patent 6153632 – Method and composition for the treatment of diabetes ‘

 Wikipedia search leads to anti-diabetic drugs, where only biguanides and glitazones are listed under insulin sensitizers . – but there is a detailed listing and discussion of the dozens of alternatives natural insulin sensitizers.

FOODS THAT HURT: agents which slow metabolism, block insulin/ sensitivity or promote fat gain -adiposity: –

cooked fats; excess ie refined sugars eg sucrose (table sugar), glucose, fructose (eg fruit juice, cornstarch); NaCl; yam, cassava, celery-seed, rosemary ; betablockers, most antidepressants and major anxiolytics; cortisone; alcohol; HGH; synthetic sex hormones, aspartame; cholesterol-lowering drugs (statins lower testosterone, impair muscle, mood and liver- but no chronic trials show that they reduce insulin resistance or newdiabetes); most administered antidiabetic drugs (eg sulphonylureas, insulin/insulin mimetics eg gliptins) except metformin (& perhaps glimepiride). Sulphonylureas (relative to metformin) increase mortality by 43% & CVD mortality by 70% (DARTS 2006).

FOODS THAT HEAL: Combine fibre with the abundant metabolic stimulants that reduce insulin resistance, adiposity, appetite, calorie absorption, cell damage & lipidemia-

The VITAMINS – A, B2, B3, B5, B6, B7, B8, B9, B12, C, D, E, K;

The MINERALS – Ca, Mg, K, Zn, Cr, Se, Va, Zn;

The BIOLOGICALS fish oil, MCT, ribose; CoQ10; alpha-lipoic acid; arginine; 5HTP, carnitine; carnosine; n-acetyl cysteine, testosterone, estradiol; melatonin; inositol; GABA; taurine; thyroid;

the drug metformin derived from the plant galega biguanide ;and at least 66 other plants incl. aloe; sutherlandia; barley; basil; cinnamon, garlic, onion, cabbage, cucumber, spinach, nettle, white sweet potato,  gymnema, coleus, indigofera, fenugreek, curcumin, ginseng, olive leaf, dandelion, bilberry, kidneybean, stevia, psyllum, milk thistle, – see Pubmed on individual nutrients, and Hyperglycemic and Hypoglycemic Herbs .

Few of the above are commonly perceived staple foods; but they are easily combined – at modest dose and cost – in a twice daily food supplement regime. Since they combat all disease, there is hardly longer justification for using even the prescription drug metformin, let alone other (futile, risky) heavily marketed drugs- except that with rising demand, unless one grows one’s own foodstuffs, natural herbs and refined micronutrients especially in multiblends become far more expensive than prescription metformin. .

 In conclusion: what the Drug industry would dearly have us ignore is The Unitarian Hypothesis for the aetiology of diabetes mellitus. Morrison ea 2006 note that “over the years, insulin insufficiency will develop in most cases of even type 2 diabetes, with insulin therapy eventually required in order to achieve normoglycaemia. The Unitarian Hypothesis presents an overall cascade of biochemical and physiological interactions, a logic which embraces the points of entry of a variety of insults, all of which can lead to the clinical picture of hyperglycaemia and its attendant adverse outcomes.

The hypothesis buttresses the belief that nature – the genetic predisposition which directs potential antibody development; and nurture – the environmental influences such as stress, exercise, nutritional status (over- or under-), infective and toxic attack, can aggravate or initiate aspects of the cascade of reactions leading to hyperglycaemia. The causative agents functioning internally within the cascade are imputed to be free radicals, oxidizing molecular species and antibodies and the corollary to this overview concept would be that a situation that minimizes the genesis and accumulation of these three agents would minimize the development of diabetes mellitus.        

Currently the debate is rife about the use of free radical scavengers and antioxidants in the treatment and prevention of diabetes mellitus. The verdict is still out on this approach. Our research on rootcrops such as yams and cassava, staple foods in tropical countries, indicates the presence of cyanoglycosides such as linamarin, which on digestion yields cyanide radicals. These radicals are pancreatotoxic especially in the undernourished state. Dog models however, have shown that free radical scavengers such as riboflavin, Vitamin B2, is protective against this toxic damage. Further, scientific investigations have clearly demonstrated the role of antibody attack and have been able to ward off the appearance of type 1 diabetes mellitus in susceptible individuals, by the early use of immunosuppressive therapy such as cyclosporin.

Thus the Unitarian Hypothesis demonstrates how all types of clinical syndromes being described in diabetes mellitus are not necessarily variants of a specific illness but rather manifestations of a central process of membrane damage→antibody response→insulin inadequacy (quantitatively or qualitatively); and the future intervention in containing this disease may well lie in focusing on preservation of the integrity of the body’s cell membranes.”

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One response to “LISTING THE SCORES OF NATURAL WEIGHT-REDUCING INSULIN SENSITIZERS:

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