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Entries tagged as ‘insulin resistance’

OBESITY AND DIABETES ARE NOT GENETICALLY INEVITABLE.

February 7, 2008 · No Comments

Health headlines from BBC the past week are ironically contradictory, but not inevitable profits of gloom.

Sugar- including cane sugar and excess fruit sugar- and cooked/processed fat – are perhaps the greatest slow “foodstuff” poisons commercialised and concentrated by “civilization”.
The industrial society and it’s omnipresent (TV- cellphone) media deliberately ruin children’s health by introducing them early to profitable sweeteners, cooked fats, fast food, TV and computer addictions, instead of natural fresh foods, exercise, playing and books. The inevitable tidal wave of obesity and chronic degenerative disease then becomes further wealth- The Disease Industry for whom Only Disease Pays. .

Obesity may thus be partly genetic, but is not inevitable with sensible habits:
A new twin study from UK found that “Becoming overweight as a child is more likely to be the result of genes than lifestyle”. http://news.bbc.co.uk/2/hi/health/7230065.stm.

But as the Child Growth Foundation says: “Even if someone has a gene which predisposes them to obesity, it doesn’t mean they will become obese if they work hard to eat healthily” . The National Centre for Eating Disorders carefully analyses how much can be done by the individual to reduce genetic risk http://www.eating-disorders.org.uk/docs/obesity.doc .

The only safe intense sweeteners are those which are both plant-sourced and which reduce insulin resistance – eg stevia. The artificial sweeteners that have been proven 100% safe are cyclamate-saccharine - but they do not reduce insulin resistance.

The only OBESITY “drug” that has been proven in major trials and long term follow up to reduce all major chronic diseases and premature deaths – by 1/3- and HALVE new diabetes (and thus cholesterol-lipid- problems) when started well before overweight and hypertension are established, is the 80year old plant extract METFORMIN. This is THE ONLY widely available low cost prescription drug that safely produces an average of 8% weight loss sustained for as long as it is taken consistently at tolerated dose.
In Canadian experience, metformin halves all deaths in type 2 diabetics followed up for a decade; and in preventative trials, it approximately halves the incidence of new type 2 diabetes. Metformin is 100% safe provided it is started at low dose eg ~125mg/day- and increased gradually over 2 weeks to the maximum dose that is well tolerated without excessive diarrhoea, nausea, abdominal bloating or pain. This dose averages about 2.5gms a day in westerners, but (due to genetic variation) may be as low as 250mg/day. It should always be stopped briefly with any acute symptoms or acute illness, and resumed at a tolerated lower dose. It must thus always be taken in consultation with a health professional.
It is understandably rarely promoted by the Disease Industry because it is out of patent, too cheap- and it work too well. For this profitable Industry, Only Disease Pays! So only expensive new drugs are heavily promoted.

Due to the destructive combination of stressful indolence- hours spent every day watching TV instead of playing outside/ sport- and stress (cortisol) and fast food stuffed with sugar and fat, even preteen children (never mind adults at all ages) suffer increasingly from overweight and teenage type 2 diabetes, and girls from polycystic ovary- infertility-hairiness problems.

Synthetic patent weight-reducing and anti-diabetic drugs eg sbutramine, orlistat, the glitazones, have major adverse effects, and have none of the global long term advantages of metformin. The only reason for their prescription is the intensive drug industry marketing imperative.

Apart from correcting the causes outlined above, preventing and treating overweight and diabetes can be easily achieved with a permanent safe low cost natural multicombination of supplements like appetite- and insulin-resistance reducing agents eg vitamins, minerals and biologicals eg metformin/galega, 5HTP, and fish oil tailored to individual tolerance. http://www.ajcn.org/cgi/content/full/83/6/S1499?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=1&title=n-3+fatty+acids+and+the+metabolic+syndrome.&andorexacttitle=and&andorexacttitleabs=and&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT

Health advisors who argue against this are rarely un-informed, they have usually chosen ( for profit) to promote drug industry new drugs rather than healthy truth. The Disease Industry will never invest in trials to prove the obvious, since the supplements are not patentable ie not profitable. So they pay cynical lobbyists to argue loudly that such evidence-based natural safe supplements must first be proven in vast longterm trials - although such trial proof is not required for new designer drugs by the Regulators eg the FDA, Medicines Control Councils who are funded by the drug industry! And politicians, governments don’t argue because the drug industry is a huge creator of jobs and revenue.

Modern drugs for chronic disease allowed by the FDA to be freely prescribed are withdrawn only when enough people die: The Americans have just had to stop the glitazone arm of the massive ACCORD trial in diabetics after 25% more deaths occurred on Avandia than in controls. http://www.msnbc.msn.com/id/23029191/. But- lo and behold- there is still no announcement yet about the withdrawal of the unnecessary glitazones that have no overall longterm health benefit except for the investors!.

http://news.bbc.co.uk/1/hi/health/7219315.stmLast
Thursday, 31 January 2008, 10:27 GMT
Obesity drug use rises eight-fold
Obesity levels are increasing
More than 1m prescriptions are made for obesity drugs a year - eight times the number dispensed seven years ago. The majority of these were for two treatments - sibutramine and orlistat.

http://news.bbc.co.uk/1/hi/health/7219473.stm
Friday, 1 February 2008, 00:14 GMT
Gout surge blamed on sweet drinks

Categories: diabetes prevention · overweight prevention · supplements
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STATINS- THE HARMFUL (AND LARGELY UNNECESSARY) MARKETTED CHOLESTEROL-LOWERING DRUGS

February 5, 2008 · No Comments

THE HARMFUL (AND LARGELY UNNECESSARY) MARKETTED CHOLESTEROL-LOWERING DRUGS

A new study from Texas University (Riechman SE ea, Statins and dietary and serum cholesterol are associated with increased lean mass following resistance training. J Gerontol A Biol Sci Med Sci. 2007;62:1164-71) shows that the cholesterol-busting statins significantly increase muscle mass. But the authors carefully analyze why this did not translate to increase in muscle strength. In fact many studies show that these drugs cause muscle damage- pain and fatigue, weakness – in up to 25% of users – especially with exercise - perhaps especially where there is pseudohypertrophy, which is probably what Riechman ea saw, muscle swelling from statin-induced damage..

This contrasts with physiological human androgen (testosterone) which cause genuine increase in both lean mass and strength (independent of exercise, and far more so with exercise), whether in bodybuilders or in the frail elderly (Bhasin ea 1996 et seq). Statins predictably cause the reverse- muscle damage pseudohypertrophy associated with significant fall in androgen levels, depression, impotence, lung, liver and kidney damage…

Contrary to the hype of the marketing industry (which funds the Regulators – FDA, Governments, Academics and the vast Disease Industry through “research” grants, taxes, jobs and congresses), there is no good reason to take or prescribe routine statins since evidence does not support their benefit EXCEPT in rare severe hypercholesterolemia. Cholesterol is not the cause of disease, it is a key biological building block – common mild to moderate lipidemia is mostly a manifestation of simple dysmetabolism, mostly insulin resistance from lack of exercise and a few score micronutrients that are safely, easily and cheaply supplemented .

The creation of the non-existent hypercholesterolemia epidemic to sell statins is well described by Dr James le Fanu in The Rise and Fall of Modern Medicine: Abacus, London, 1999;
and was mimicked a decade later by Pfizer in fabricating a pandemic of impotence to create a market for the potentially blinding/ killer blockbuster arrhythmogenic Viagra sildenafil – which is rarely needed if the common relative androgen and other micronutrient deficiency of aging is simply screened for and appropriately corrected at trivial cost and no risk, with global health benefits.
It is common cause that sexuality (in both genders) starts declining as the serum testosterone falls below the average level of healthy youth – but Pfizer and the FDA have colluded tenaciously to conceal this fact in refusing for years to disclose the mean and range of testosterone levels of the men who were included in the infamous Viagra trials. Yet simple testosterone, magneium and fish oil are the major antiarrhythmic drugs- and most people die suddenly, from arrhythmia as the terminal event.

Antimicrobials aside, statins and all other modern drugs for chronic prevention are designed to target symptoms, not the root cause of diseases- so modern chronic drugs do not significantly reduce all-cause mortality and common major diseases of aging. The last thing the trillion-dollar Disease Industry wants is effective cheap prevention that can reduce by 90% the need for modern drugs, high-tech investigations and admissions to hospitals.

So the Disease Industry and it’s myriad beneficiaries – shareholders and staff, the FDA, Governments, academics, clinicians and politicians everywhere- desperately want to suppress and regulate access to and supply of the simple safe combination of natural proven drugs – the nutritional supplements like appropriate niacin, fish oil, and a few score other vitamins, minerals and biologicals (mostly also insulin sensitizers like appropriate sex hormone replacement/HRT, metformin/ galega etc) Together these unprofitable old drugs do vastly better in halving all common major chronic degenerative diseases of aging than fraudulent wannabe designer patent drugs like statins (and non-steroidal, anti-osteoporosis, anti-diabetics, anti-obesity, anti-depressants, and hormone substitutes) that are allowed by Regulators (like Congress and politicians everywhere, the tool of the lucrative drug industry – Only Disease Pays) to poison millions - the Innocent Survivors - Elaine Feuer’s famous 1997 expose..

AND Just in case you thought statins were “benign” drugs…. from the University of Cape Town Drug Info Centre-
The February 2008 issue of ‘Drug Safety Update’ from the MHRA notes that product information for statins is being updated to reflect a number of different side-effects which appear to be a class-effect of these medicines. The following prescribing advice is given:

• Patients should be made aware that treatment with any statin may sometimes be associated with depression, sleep disturbances, memory loss, and sexual dysfunction

• Statins may very rarely be associated with interstitial lung disease. Patients should seek help from their doctor if they develop presenting features of interstitial lung disease such as dyspnoea, non-productive cough, and deterioration in general health (e.g., fatigue, weight loss, and fever)

so, why take statins? unless you have severe lipidemia, stop them, take supplements that are far better. But discuss this with your doctor.

ndb

Categories: HRT · diabetes prevention · overweight prevention · supplements
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